Vidal-Gadea Lab

School of Biological Sciences, Illinois State University

People

Eleven people are working in the lab this semester, on parts of one problem rather than on eleven problems, with one more joining in the spring.

The work interlocks by design. Mackenzie acquires the calcium recordings. Keke curates them against WINK, using the modules Chandler writes. Marcos is building the edited cell line the calcium work needs, so that anything found can be attributed to dystrophin. He and Nora score the same muscle cells independently, so human and machine can be compared. Naga is asking in smooth muscle the question Danny answered in striated. That is why people here appear on each other's papers.

Portraits are painted rather than photographed, a house style we adopted so that everyone appears the same way.

Principal investigator

Photograph of Andres Vidal-Gadea Andrés Vidal-Gadea, PhD Professor of Molecular Neuroethology. Graduate Program Coordinator for the Physiology, Neuroscience and Behavior sequence. Works at the join between biology and physics. How does a genetic lesion change muscle's ability to withstand mechanical load, and how does a nervous system read a magnetic field? Outstanding University Researcher 2025, Outstanding College Researcher 2024, Faculty Mentor Award from the Louis Stokes Alliance for Minority Participation 2018. Curriculum vitae (PDF).

Graduate students

Photograph of Damiano Marchiafava Damiano Marchiafava, PhD Defended October 2026, in the lab through December. Built the lab's human muscle cell branch from nothing. He taught himself culture, differentiation and editing of human muscle cells. His dissertation covers the calcium set point of dystrophic muscle, and the fibrillin related proteins that help hold it. He also served as head TA for introductory biology labs.
Photograph of Mackenzie Jones Mackenzie Jones MS candidate and the lab's lead worm person. Runs the multi-channel live calcium imaging on the confocal. Owns the RGBCaMP reporter work, comparing calcium kinetics across muscle compartments in healthy and dystrophic animals. Carries the dystrophin isoform experiments, and has begun mouse muscle dissection.
Photograph of Naga Nidadavolu Naga Nidadavolu Graduate student on smooth muscle, in both human cells and the worm. Runs calcium imaging of smooth muscle myoblasts under pharmacological stimulation. Her question is whether the calcium defects found in striated muscle appear in smooth muscle too. Smooth muscle is the newest arm of the program.

Undergraduate researchers

Photograph of Nora Armstrong Nora Armstrong Co-author on the study of animals raised for six generations under Mars analog gravity and hypomagnetic fields. She ran its revision experiments. She now outlines muscle cells for the lab's human to machine comparison.
Photograph of Marcos Perez-Rodriguez Marcos Perez-Rodriguez Using CRISPR to build an isogenic dystrophic human muscle cell line. It starts from the same healthy line used in the lab's calcium set point work, so the two differ in one gene and nothing else. He is also an independent scorer on the muscle cell manuscript.
Photograph of Keke Velez Keke Velez Runs the worm hotel, filming single animals performing distinct muscle specific behaviors, and curates the resulting recordings against WINK's output, correcting frames the machine gets wrong. Ran an RNA interference screen for genes that alter branching in muscle.
Photograph of Chandler Huffman Chandler Huffman Writes the lab's Python worm tracker and WINK analysis modules. She is writing the technical manuscript describing them, as first author. A Division I student-athlete, heading for a PhD in biomedical engineering.
Photograph of Brooke Stewart Brooke Stewart Working on rescue of a calcium pump in dystrophic animals. She designed the long range PCR primers that amplify the genomic locus for the rescue construct.
Photograph of Angelina Vera Angelina Vera Undergraduate researcher on the Duchenne muscular dystrophy program.
Photograph of Elyssa Guleng Elyssa Guleng Undergraduate researcher on the Duchenne muscular dystrophy program.
Photograph of Ava Carroll Ava Carroll Joined in Fall 2026 on the Duchenne muscular dystrophy program, learning the worm assays and the calcium imaging workflow.

Before you write to someone

If you are a prospective student, write to Andrés rather than to a lab member. If you are looking for a former member, the alumni page records where people went.