Vidal-Gadea Lab Research Impact Dashboard

Professor Andrés G. Vidal-Gadea, Ph.D.
School of Biological Sciences, Illinois State University
Last updated: November 2026
2015
Started Lab
Assistant Professor
2020
Promoted
Associate Professor
2025
Promoted
Full Professor
31
Peer-reviewed publications
ISU publications page, Oct 2026
1,046
Citations
Google Scholar. OpenAlex gives 756 (Nov 2026)
15
h-index
Google Scholar. OpenAlex gives 13 (Nov 2026)
$2.0 M
Research funding as PI
$2,004,842, verified Oct 2026

Research Philosophy

Our lab investigates how animals interact with the physical world. We focus on specific physical variables that living systems must detect, respond to, and survive: mechanical forces, magnetic fields, gravity, and temperature. We ask how animals sense these parameters, how they generate and withstand forces, and what happens when these systems fail in disease.

Understanding these interactions requires developing new approaches to measure and manipulate them. Our lab builds behavioral assays, measurement systems, and molecular tools that enable quantitative analysis of organism-environment interactions. This approach bridges basic discovery with translational applications to neuromuscular disease and extreme environments.

1
Physical Interactions
Which physical parameters matter to living systems?
Mechanical forces, magnetic fields, gravity, temperature. The subset of physics that organisms evolved to detect and respond to.
2
Mechanisms & Pathology
How do these interactions work, and what happens when they fail?
Sensory transduction (magnetosensation, mechanoreception, thermosensation). Force generation (muscle contraction, locomotion). Disease states (DMD, calcium dysregulation).
3
Tools & Methods
Developing approaches to measure and manipulate
Novel behavioral assays, measurement systems, molecular reporters, mathematical models. Open access tools and protocols for research and education.

Research Tools & Innovation

Behavioral Assays
Swim/crawl transition assay (PNAS 2011), burrowing assay for neuromuscular integrity (2015), magnetic orientation tracking systems. Custom measurement approaches for natural behaviors.
Instrumentation
Custom magnetic coil systems (multiple configurations for field manipulation), magnetic pulse generators, WormBot adaptation for high throughput analysis, affordable worm tracker (open access design).
Human Muscle Physiology System (2025)
Integrated system for force measurement, calcium imaging, and temperature control in 3D human skeletal muscle constructs. Synchronized electrical stimulation with multi-modal data acquisition.
Molecular Tools
RGBCaMP multi-compartment calcium reporter (simultaneous cytoplasm, mitochondria, SR imaging), thermosensitive fluorescent reporters, complete dystrophin knockout strains (VG02/VG03), CRISPR generated dystrophic human myoblasts.
Method Dissemination
Published protocols and book chapters, open access designs and code, YouTube video library (71 videos, 36K views), comprehensive training materials for 216+ students.

Recent Awards and Recognition

2025
Outstanding University Researcher, Illinois State University
2024
Outstanding College Researcher, Illinois State University
2021
Million Dollar Club, Illinois State University
2020
Researchers to Know, Illinois Science & Technology Coalition
2019
Research Initiative Award, Illinois State University
2018
Outstanding STEM Professional Award, McLean County Chamber of Commerce
2018
Faculty Mentor Award, Louis Stokes Alliance for Minority Participation

Recent Publications

Behavioral deficits in C. elegans raised for six generations under Mars-analog gravity and hypomagnetic fields
Akinosho A, Armstrong N, Benefield Z, Dai X, Stein W, Vidal-Gadea AG
Activity-dependent remodeling of muscle architecture during distinct locomotor behaviors in C. elegans
Fazyl A, Anbu A, Kollbaum S, Vidal-Gadea AG
Fibrillin-Related Proteins Control Calcium Homeostasis in Dystrophic Muscle Across Species
Marchiafava D, Vidal-Gadea AG
microPublications Biology (2025)
Independent Validation of Transgenerational Inheritance of Learned Pathogen Avoidance in C. elegans
Akinosho A, Alexander J, Floyd K, Vidal-Gadea AG
eLife (2025)

High-Impact Publications

Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy
Hughes K, Rodriguez A, Flatt K, et al., Vidal-Gadea AG
PNAS (2019) - Featured in Medical Xpress
Magnetosensitive neurons mediate geomagnetic orientation in C. elegans
Vidal-Gadea AG, Ward K, Beron C, et al., Pierce-Shimomura JT
eLife (2015) - Featured in Nature Reviews, NPR, Scientific American
C. elegans selects distinct crawling and swimming gaits via dopamine and serotonin
Vidal-Gadea AG, Topper S, Young L, et al., Pierce-Shimomura JT
PNAS (2011) - Featured in Scientific American, CBS News
Coding characteristics of spiking local interneurons during imposed limb movements in the locust
Vidal-Gadea AG, Jing XJ, Simpson D, et al., Newland PL
Journal of Neurophysiology (2010) - Wiener kernel mathematical modeling

Active Research Grant

NIH R15 (NIAMS)
2026-2029 | $544,734.00 | Genetic repair of muscular degeneration associated with Duchenne muscular dystrophy

Research Programs

Duchenne Muscular Dystrophy
Investigating pathophysiology using C. elegans and human myocyte models. Developed first cross-tissue DMD model and complete dystrophin knockout strains. Building force and calcium measurement systems for human muscle constructs.
Mechanotransduction
Studying how organisms detect and respond to mechanical forces. PEZO-1 mechanoreceptors in muscle function, locomotion, and feeding. Proprioceptive systems in locusts using Wiener kernel analysis.
Magnetic Field Bionavigation
Pioneering work on nematode magnetosensation. Identified magnetosensitive neurons and investigating molecular mechanisms. Custom magnetic coil systems and pulse generators for mechanism discovery.
Neuromuscular Systems
Motor control, muscle plasticity, and neuromuscular communication. Novel behavioral assays for neuromuscular integrity. Gait selection mechanisms via neuromodulators.
Astrobiology Research
Investigating multigenerational effects of simulated Martian conditions (reduced gravity and hypomagnetic fields) on C. elegans. Custom systems to manipulate physical parameters of extraterrestrial environments.
Crustacean Neurogenetics
Developing first genetic tools for decapod neuroscience using marbled crayfish. Collaboration exploring neuromodulation and neural network dynamics.

Citation Growth

Student Mentoring Excellence

Transformative Educational Impact (2015-2026)

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People trained since 2015
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Alumni whose destination is recorded
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Of those, continued in STEM
17 of 23
Lab papers with a trainee as first author

These figures are read live from the roster that drives the lab website, so this page and that one cannot disagree. No national benchmark exists for trainees mentored at any institutional tier, so no comparison is offered here.

View alumni and outcomes on the lab website

Where this record sits

Publication position. 16 journal articles 2015 to 2026 in life science fields carrying an Illinois State affiliation. Among the 98 Illinois State authors with five or more such articles, the median is 7 and the 90th percentile is 16. Pooled across nine Midwest public doctoral comprehensives, 507 authors, the figure sits at the 92.7th percentile.

Against research intensive universities. An h-index of 12 is reached by 7.0 percent of life science authors at Illinois State and by 11.6 to 14.0 percent at six large research universities, so the same record would sit near the 88th percentile there. Output per senior investigator is 7.1 articles here against 5.3 to 9.6 across those six. The difference in total output between institution types is mostly a difference in how many laboratories there are.

Output per dollar. NIGMS reports that the median investigator holding an R01 or P01 runs $220,000 in annual direct costs and publishes 1.71 papers a year. This laboratory runs $145,117 a year and publishes 2.09, which is at least 1.85 times the publications per funded dollar. At least, because the NIGMS figure is direct costs and this one is total award dollars.

Authorship. 71 percent of papers in the window are first or last authored, against a median of 50 percent among the 63 senior life science authors at this institution.

Every figure above is reproducible from the queries recorded in VGL_BENCHMARKING_REFERENCE. Sources: OpenAlex, NIH RePORTER, NIGMS Feedback Loop. Student mentoring has no national benchmark and is reported in absolute terms only.

Media Coverage and Science Communication

Major Media Features
NPR, NBC News, Scientific American, Nature Reviews, The Scientist, Medical Press, RAI (Italy), El País (Uruguay), Pantagraph, 25News
Digital Science Communication
71+ research videos on YouTube with 36,000+ views, comprehensive web portfolio, interactive research dashboards, science outreach coloring book
Public Engagement
Regular K-12 science education programming, podcast appearances, community science events, educational resource development